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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Swaminathan FrontInGenetics2018 9.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Wang BMCMedInfoDecMak2019 19-1.png|240px]]</div>
'''"[[Journal:Transferring exome sequencing data from clinical laboratories to healthcare providers: Lessons learned at a pediatric hospital|Transferring exome sequencing data from clinical laboratories to healthcare providers: Lessons learned at a pediatric hospital]]"'''
'''"[[Journal:Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory|Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory]]"'''


The adoption rate of [[Genomics|genome sequencing]] for clinical diagnostics has been steadily increasing, leading to the possibility of improvement in diagnostic yields. Although [[Laboratory|laboratories]] generate a summary clinical report, sharing raw genomic data with healthcare providers is equally important, both for secondary research studies as well as for a deeper analysis of the data itself, as seen by the efforts from organizations such as American College of Medical Genetics and Genomics, as well as Global Alliance for Genomics and Health. Here, we aim to describe the existing protocol of genomic data sharing between a certified [[clinical laboratory]] and a healthcare provider and highlight some of the lessons learned. This study tracked and subsequently evaluated the data transfer workflow for 19 patients, all of whom consented to be part of this research study and visited the genetics clinic at a tertiary pediatric hospital between April 2016 and December 2016. ('''[[Journal:Transferring exome sequencing data from clinical laboratories to healthcare providers: Lessons learned at a pediatric hospital|Full article...]]''')<br />
n autoverification system for coagulation consists of a series of rules that allows normal data to be released without manual verification. With new advances in [[medical informatics]], the [[laboratory information system]] (LIS) has growing potential for the use of autoverification, allowing rapid and accurate verification of [[clinical laboratory]] tests. The purpose of the study is to develop and evaluate a LIS-based autoverification system for validation and efficiency.
 
Autoverification decision rules—including quality control, analytical error flag, critical value, limited range check, delta check, and logical check rules, as well as patient’s historical information—were integrated into the LIS. Autoverification limit ranges was constructed based on 5% and 95% percentiles. The four most commonly used coagulation assays—prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (FBG)—were followed by the autoverification protocols. ('''[[Journal:Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory|Full article...]]''')<br />
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Revision as of 15:52, 11 November 2019

Fig1 Wang BMCMedInfoDecMak2019 19-1.png

"Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory"

n autoverification system for coagulation consists of a series of rules that allows normal data to be released without manual verification. With new advances in medical informatics, the laboratory information system (LIS) has growing potential for the use of autoverification, allowing rapid and accurate verification of clinical laboratory tests. The purpose of the study is to develop and evaluate a LIS-based autoverification system for validation and efficiency.

Autoverification decision rules—including quality control, analytical error flag, critical value, limited range check, delta check, and logical check rules, as well as patient’s historical information—were integrated into the LIS. Autoverification limit ranges was constructed based on 5% and 95% percentiles. The four most commonly used coagulation assays—prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (FBG)—were followed by the autoverification protocols. (Full article...)

Recently featured:

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