Template:Past, Present, and Future of Cannabis Laboratory Testing and Regulation in the United States/Laboratory testing of cannabis/Methods and guidelines/Sampling
Random, representative sampling is encouraged. When dealing with solid cannabis, BOTEC Analysis recommends a "quartering" method that divides the sample into four equal parts and takes portions from opposite sections of a square-shaped arrangement of the sample. For liquid cannabis products, remembering to stir before sample collection is advised.[1] Sampling techniques may also vary depending on the constituent being tested, as with terpene testing, which may favor full evaporative technique (FET) headspace-based (HS) sampling for reducing certain sampling biases.[2] Another consideration may be the matrix being tested, as when deriving a sample from a cannabis-laden edible; the QuEChERS approach used by food safety labs for pesticide testing may have practical use.[3] In fact, a variety of parallels have been drawn from the food and herbal medicine industries' sampling guidelines, including from the Codex Alimentarius Commission's CAC/GL 50-2004 General Guidelines on Sampling as well as various chapters of the United States Pharmacopeia and The National Formulary.[1][4] As the Association of Public Health Laboratories (APHL) points out, "[g]ood sampling is key to improving analytical data equivalency among organizations," and it provides a solid base for any future testing and standardization efforts.[1]
Additional sampling insight can be found by examining other states' guidelines, e.g., Massachusetts' Protocol for Sampling and Analysis of Finished Medical Marijuana Products and Marijuana-Infused Products for Massachusetts Registered Medical Marijuana Dispensaries[5], as well as ASTM D8334/D8334M-20 Standard Practice for Sampling of Cannabis/Hemp Post-Harvest Batches for Laboratory Analyses.[6]
- ↑ 1.0 1.1 1.2 Association of Public Health Laboratories (May 2016). "Guidance for State Medical Cannabis Testing Programs" (PDF). pp. 35. https://www.aphl.org/aboutAPHL/publications/Documents/EH-Guide-State-Med-Cannabis-052016.pdf. Retrieved 05 August 2022.
- ↑ Goldman, Stephen; Bramante, Julia; Vrdoljak, Gordon; Guo, Weihong; Wang, Yun; Marjanovic, Olivera; Orlowicz, Sean; Di Lorenzo, Robert et al. (15 June 2021). "The analytical landscape of cannabis compliance testing" (in en). Journal of Liquid Chromatography & Related Technologies 44 (9-10): 403–420. doi:10.1080/10826076.2021.1996390. ISSN 1082-6076. https://www.tandfonline.com/doi/full/10.1080/10826076.2021.1996390.
- ↑ Rigdon, A. (12 May 2016). "Extraction Method for Cannabinoid Analysis in Edibles: Too Much of a Good Thing". ChromaBLOGraphy. Restek Corporation. Archived from the original on 19 September 2017. https://web.archive.org/web/20170919014255/http://blog.restek.com/?p=25790. Retrieved 05 August 2022.
- ↑ Codex Alimentarius Commission. "CAC/GL 50-2004 General Guidelines on Sampling" (PDF). pp. 69. Archived from the original on 28 April 2019. https://web.archive.org/web/20190428175411/http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FStandards%252FCAC%2BGL%2B50-2004%252FCXG_050e.pdf. Retrieved 05 August 2022.
- ↑ Bureau of Health Care Safety and Quality (5 February 2016). "Protocol for Sampling and Analysis of Finished Medical Marijuana Products and Marijuana-Infused Products for Massachusetts Registered Medical Marijuana Dispensaries" (PDF). Massachusetts Department of Public Health. pp. 25. Archived from the original on 08 September 2017. https://web.archive.org/web/20170908014040/http://www.mass.gov/eohhs/docs/dph/quality/medical-marijuana/lab-protocols/finished-mmj/final-revised-mdph-mmj-mips-protocol.pdf. Retrieved 05 August 2022.
- ↑ ASTM Subcommittee D37.03 (1 December 2020). "ASTM D8334/D8334M-20 Standard Practice for Sampling of Cannabis/Hemp Post-Harvest Batches for Laboratory Analyses". ASTM International. https://www.astm.org/d8334_d8334m-20.html. Retrieved 05 August 2022.
