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AB Sciex Pte. Ltd.

Main landing page for cannabis testing: https://sciex.com/applications/food-and-beverage-testing/cannabis-testing

Commonly known as Sciex, AB Sciex Pte. Ltd. develops "solutions in mass spectrometry paired with capillary electrophoresis and liquid chromatography."[1] The company markets some of its solutions for cannabis lab testing, including[2]:

  • pesticide testing
  • potency testing
  • mycotoxin testing
  • terpenes testing

Instruments

Triple Quad systems

Sciex offers four different Triple Quad systems for LC-MS/MS: the 6500+, 5500, 4500, and 3500.

6500+

The 6500+ has the following key features, per the website[3]:

Mass Range: 5-2000 Da

Features: IonDrive QJet, HED Detector

Detector Type: IonDrive High Energy Detector+

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM, EMS, EPI, ER, MS3, MRM3

Ionization Sources/Options: IonDrive Turbo V; OptiFlow™ Turbo V; TurboIonSpray®; Atmospheric-pressure chemical ionization (APCI); DuoSpray™, and NanoSpray® III, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource, SelexION®+

5500

The 5500 has the following key features, per the website[4]:

Mass Range: 5-1250 Da

Features: Turbo V, Pulse Counting Detector

Detector Type: AcQuRate Pulse Counting Detector

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM

Ionization Sources: Turbo V, OptiFlow Turbo V, TurboIonSpray® Atmospheric-pressure chemical ionization (APCI); DuoSpray™, and NanoSpray® III, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource, SelexION®

4500

The 4500 has the following key features, per the website[5]:

Mass Range: 5-2000 Da

Detector Type: AcQuRate Pulse Counting Detector

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM

Ionization Sources: Turbo V; TurboIonSpray; Atmospheric-pressure chemical ionization (APCI); DuoSpray®, and NanoSpray® III

3500

The 3500 has the following key features, per the website[6]:

Mass Range: 5 – 2000 Da

Features: Turbo V, Pulse Counting Detector

Detector Type: AcQuRate Pulse Counting Detector

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM

Ionization Sources: TurboV ion source with TurboIonSpray™ and APCI probes

QTRAP systems

Sciex also offers three different Triple Quad Linear Ion Traps (QTRAP) systems for LC-MS/MS: the 6500+, 5500, and 4500. The company states that these are similar to the Triple Quad systems "but with enhanced scan functions to enable simultaneous quantitation and confirmation."[7]

QTRAP 6500+

The QTRAP 6500+ has the following key features, per the website[8]:

Mass Range: Dual switchable mass range: up to 1250 Da or up to 2000 Da

Features: IonDrive QJet, HED Detector

Detector Type: IonDrive High Energy Detector+

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap™ Scanning

Ionization Sources/Options: IonDrive Turbo V; OptiFlow™ Turbo V; TurboIonSpray®; Atmospheric-pressure chemical ionization (APCI); DuoSpray™, and NanoSpray® III, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource, SelexION®+

QTRAP 5500

The QTRAP 5500 has the following key features, per the website[9]:

Mass Range: Dual mass range Up to 1250 Da

Features: Turbo V, Turbo V OptiFlow™, Pulse Counting Detector

Detector Type: AcQuRate Pulse Counting Detector

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap™ Scanning

Ionization Sources: Turbo V OptiFlow™, TurboIonSpray Atmospheric-pressure chemical ionization (APCI); DuoSpray™, and NanoSpray® III, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource, SelexION®

QTRAP 4500

The QTRAP 4500 has the following key features, per the website[10]:

Mass Range: Up to 2000 Da

Features: Turbo V, Pulse Counting Detector

Detector Type: AcQuRate Pulse Counting Detector

Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap Scanning

Ionization Sources: Turbo V; TurboIonSpray; Atmospheric-pressure chemical ionization (APCI); DuoSpray®, and NanoSpray® III, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource

vMethod for Cannabis

Sciex also offers a "vMethod," a quantitation method for pesticide and cannabinoid analysis, that works on many of their LC-MS/MS systems.[11]

References

  1. "About Us". AB Sciex Pte. Ltd. https://sciex.com/about-us. Retrieved 20 November 2018. 
  2. "Grow Your Cannabis Lab's Potential and Bottom Line with LC-MS/MS Analysis". AB Sciex Pte. Ltd. https://sciex.com/applications/food-and-beverage-testing/cannabis-testing. Retrieved 20 November 2018. 
  3. "SCIEX Triple Quad 6500+ LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-6500plus-system. Retrieved 21 November 2018. 
  4. "SCIEX Triple Quad 5500 LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-5500-system. Retrieved 21 November 2018. 
  5. "SCIEX Triple Quad 5500 LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-4500-system. Retrieved 21 November 2018. 
  6. "SCIEX Triple Quad 5500 LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-3500-system. Retrieved 21 November 2018. 
  7. "QTRAP LC-MS/MS Systems". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/qtrap-systems. Retrieved 21 November 2018. 
  8. "QTRAP 6500+ LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/qtrap-systems/qtrap-6500plus-system. Retrieved 21 November 2018. 
  9. "QTRAP 5500 LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/qtrap-systems/qtrap-5500-system. Retrieved 21 November 2018. 
  10. "QTRAP 4500 LC-MS/MS System". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/qtrap-systems/qtrap-4500-system. Retrieved 21 November 2018. 
  11. "vMethod Application for Quantitation of Pesticide Residues and Cannabinoids in Cannabis Matrices 1.0". AB Sciex Pte. Ltd. https://sciex.com/products/methods/vmethod-application-for-quantitation-of-pesticide-residues-and-cannabinoids-in-cannabis-matrices-10. Retrieved 21 November 2018.