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Table 3 lists the major vendors developing and selling PCR, isothermal amplification, and NGS supplies, instruments, and software for both clinical diagnostics and life science research. "Research use only" equipment like Siemens Healthcare's Fast Track Cycler was ignored for completing the table. The vendor list was largely compiled from vendors identified in a handful of online market reports on PCR, with an added sprinkling of a few additional reagent vendors (e.g., Jena Bioscience, LGC, and New England BioLabs) who address isothermal amplification supplies in addition to PCR. Note that this is not an endorsement for any particular vendor.

Table 3. Major players operating in the global diagnostic PCR, isothermal amplification, and NGS market Vendor Shop all products PCR machines Nucleic acid extraction and purification machines Immunoassay analyzers and assays PCR and qPCR assays PCR and qPCR enzymes and master mixes DNA/RNA purification, quantitation, and amplification supplies LAMP assays Isothermal amplification enzymes and master mixes NGS supplies Supporting labware and supplies Software Abbott Abbott products ✓ - - ✓ ✓ - - - - ✓ ✓ Agilent Technologies Agilent products ✓ - - ✓ ✓ ✓ - - ✓ ✓ ✓ Becton, Dickinson and Company BD products ✓ - - ✓ - - - - - ✓ - Bio-Rad Laboratories, Inc. Bio-Rad products ✓ - ✓ ✓ ✓ ✓ - - ✓ ✓ - bioMérieux SA bioMérieux products - ✓ ✓ ✓ - - - - - ✓ ✓ Danaher Corporation and its companies Cepheid products, Beckman Coulter products, and Beckman Life Sciences products ✓ - ✓ ✓ - ✓ - - - ✓ - F. Hoffmann-La Roche AG Roche Diagnostics products ✓ ✓ - ✓ ✓ ✓ - - ✓ - ✓ Jena Bioscience GmbH Jena Bioscience products - - - ✓ ✓ ✓ ✓ ✓ ✓ - - LGC Limited and its companies Lucigen products - - - ✓ ✓ ✓ - ✓ ✓ - - Merck KGaA Sigma-Aldrich products and Millipore Sigma products - - - ✓ ✓ ✓ - - ✓ ✓ - New England BioLabs, Inc. NEB products - - - ✓ ✓ ✓ ✓ ✓ ✓ - - Promega Promega products and catalog - ✓ - ✓ ✓ ✓ - - ✓ - - QIAGEN N.V. QIAGEN products ✓ ✓ - ✓ ✓ ✓ - - ✓ - ✓ Siemens Healthcare GmbH Siemens Healthcare products - ✓ - ✓ - ✓ - - - - ✓ Thermo Fisher Scientific, Inc. Thermo Fisher products and Fisher Scientific products ✓ ✓ - ✓ ✓ ✓ - ✓ ✓ ✓ ✓

The "Software" column of Table 3 represents whether or not the vendor offers laboratory informatics software such as a LIMS or LIS. Those vendors' solutions may or may not be tailored to handle the specific requirements of a clinical diagnostic or virology lab handling COVID-19 and other viruses. (See the next chapter for more in-depth information about working an informatics solution into COVID-19 and other viral testing workflow.) A non-endorsed, representative example of vendors who do include:

• Abbott Informatics Corporation - STARLIMS LIMS
• AgileBio - COVID-19 LC
• Autoscribe Informatics, Inc. - Matrix Covid LIMS
• BioSoft Integrators, LLC - LabOptimize LIMS for COVID-19
• CloudLIMS.com, LLC - CloudLIMS for COVID-19
• Common Cents Systems, Inc. - Apollo LIMS for COVID-19
• Comp Pro Med, Inc. - COVID-19 Rapid Deployment LIS
• Illumina, Inc. - BaseSpace Clarity LIMS for COVID-19
• Junction Concepts, Inc. - QBench
• LabLynx, Inc. - COVIDLiMS
• LabVantage Solutions, Inc. - LabVantage COVID-19 LIMS
• Physion, LLC - Ovation LIMS for COVID-19
• Sunquest Information Systems, Inc. - Mitogen LIMS for COVID-19 (PDF)
• Third Wave Analytics, Inc. - Lockbox LIMS for SARS-CoV-2 Clinical Testing

Additionally, when in-house knowledge is lacking, a consultant may be required. These consultants are meant to be representative examples of those laboratory consulting firms indicating they have the knowledge to help a laboratory with COVID-19-related testing and other issues. This list is not an endorsement for any particular consultant:

• ARUP Laboratories (Utah)
• Colaborate (Florida)
• Elite Diagnostics (North Carolina)
• Freed Associates (California)
• Lighthouse Lab Services (North Carolina)
• Optimum Healthcare IT (Florida)
• The COVID Consultants (Colorado)
• Triumverate Environmental (Massachusetts)