Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Brusniak BMCBioinformatics2019 20.png|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Niszczota EconBusRev23 9-2.png|240px]]</div>
'''"[[Journal:Laboratory information management software for engineered mini-protein therapeutic workflow|Laboratory information management software for engineered mini-protein therapeutic workflow]]"'''
'''"[[Journal:Judgements of research co-created by generative AI: Experimental evidence|Judgements of research co-created by generative AI: Experimental evidence]]"'''


Protein-based therapeutics are one of the fastest growing classes of novel medical interventions in areas such as cancer, infectious disease, and inflammation. Protein engineering plays an important role in the optimization of desired therapeutic properties such as reducing immunogenicity, increasing stability for storage, increasing target specificity, etc. One category of protein therapeutics is nature-inspired bioengineered cystine-dense peptides (CDPs) for various biological targets. These engineered proteins are often further modified by synthetic chemistry. For example, candidate mini-proteins can be conjugated into active small molecule drugs. We refer to modified mini-proteins as "optides" (optimized peptides). To efficiently serve the multidisciplinary lab scientists with varied therapeutic portfolio research goals in a non-commercial setting, a cost-effective, extendable [[laboratory information management system]] (LIMS) is/was needed. ('''[[Journal:Laboratory information management software for engineered mini-protein therapeutic workflow|Full article...]]''')<br />
The introduction of [[ChatGPT]] has fuelled a public debate on the appropriateness of using generative [[artificial intelligence]] (AI) ([[large language model]]s or LLMs) in work, including a debate on how they might be used (and abused) by researchers. In the current work, we test whether delegating parts of the research process to LLMs leads people to distrust researchers and devalues their scientific work. Participants (''N'' = 402) considered a researcher who delegates elements of the research process to a PhD student or LLM and rated three aspects of such delegation. Firstly, they rated whether it is morally appropriate to do so. Secondly, they judged whether—after deciding to delegate the research process—they would trust the scientist (who decided to delegate) to oversee future projects ... ('''[[Journal:Judgements of research co-created by generative AI: Experimental evidence|Full article...]]''')<br />
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Latest revision as of 15:26, 20 May 2024

Fig1 Niszczota EconBusRev23 9-2.png

"Judgements of research co-created by generative AI: Experimental evidence"

The introduction of ChatGPT has fuelled a public debate on the appropriateness of using generative artificial intelligence (AI) (large language models or LLMs) in work, including a debate on how they might be used (and abused) by researchers. In the current work, we test whether delegating parts of the research process to LLMs leads people to distrust researchers and devalues their scientific work. Participants (N = 402) considered a researcher who delegates elements of the research process to a PhD student or LLM and rated three aspects of such delegation. Firstly, they rated whether it is morally appropriate to do so. Secondly, they judged whether—after deciding to delegate the research process—they would trust the scientist (who decided to delegate) to oversee future projects ... (Full article...)
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