Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Tsur BioDataMining2017 10.gif|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Mishra JofNepMedAss23 61-258.png|220px]]</div>
'''"[[Journal:Rapid development of entity-based data models for bioinformatics with persistence object-oriented design and structured interfaces|Rapid development of entity-based data models for bioinformatics with persistence object-oriented design and structured interfaces]]"'''
'''"[[Journal:Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study|Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study]]"'''


Databases are imperative for research in [[bioinformatics]] and computational biology. Current challenges in database design include data heterogeneity and context-dependent interconnections between data entities. These challenges drove the development of unified data interfaces and specialized databases. The curation of specialized databases is an ever-growing challenge due to the introduction of new data sources and the emergence of new relational connections between established datasets. Here, an open-source framework for the curation of specialized databases is proposed. The framework supports user-designed models of data encapsulation, object persistence and structured interfaces to local and external data sources such as MalaCards, Biomodels and the National Center for Biotechnology Information (NCBI) databases. The proposed framework was implemented using Java as the development environment, EclipseLink as the data persistence agent and Apache Derby as the database manager. Syntactic analysis was based on J3D, jsoup, Apache Commons and w3c.dom open libraries. Finally, a construction of a specialized database for aneurysm-associated vascular diseases is demonstrated. This database contains three-dimensional geometries of aneurysms, patients' clinical information, articles, biological models, related diseases and our recently published model of aneurysms’ risk of rapture. The framework is available at: http://nbel-lab.com. ('''[[Journal:Rapid development of entity-based data models for bioinformatics with persistence object-oriented design and structured interfaces|Full article...]]''')<br />
The [[clinical laboratory]] holds a central position in patient care, and as such, ensuring accurate [[laboratory]] test results is a necessity. Internal [[quality control]] (QC) ensures day-to-day laboratory consistency. However, unless practiced, the success of laboratory [[quality management system]]s (QMSs) cannot be achieved. This depends on the efforts and commitment of laboratory personnel for its implementation. Hence, the aim of this study was to find out the knowledge of internal QC for laboratory tests among laboratory personnel working in the Department of Biochemistry, B.P. Koirala Institute of Health Sciences (BPKIHS), a tertiary care center ... ('''[[Journal:Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study|Full article...]]''')<br />
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Revision as of 18:14, 6 May 2024

Fig1 Mishra JofNepMedAss23 61-258.png

"Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study"

The clinical laboratory holds a central position in patient care, and as such, ensuring accurate laboratory test results is a necessity. Internal quality control (QC) ensures day-to-day laboratory consistency. However, unless practiced, the success of laboratory quality management systems (QMSs) cannot be achieved. This depends on the efforts and commitment of laboratory personnel for its implementation. Hence, the aim of this study was to find out the knowledge of internal QC for laboratory tests among laboratory personnel working in the Department of Biochemistry, B.P. Koirala Institute of Health Sciences (BPKIHS), a tertiary care center ... (Full article...)
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