Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Mishra JofNepMedAss23 61-258.png|220px]]</div>
'''"[[Journal:Personalized Oncology Suite: Integrating next-generation sequencing data and whole-slide bioimages|Personalized Oncology Suite: Integrating next-generation sequencing data and whole-slide bioimages]]"'''
'''"[[Journal:Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study|Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study]]"'''


Cancer immunotherapy has recently entered a remarkable renaissance phase with the approval of several agents for treatment. [[Cancer informatics|Cancer treatment platforms]] have demonstrated profound tumor regressions including complete cure in patients with metastatic cancer. Moreover, technological advances in next-generation sequencing (NGS) as well as the development of devices for scanning whole-slide bioimages from tissue sections and [[Bioimage informatics|image analysis software]] for quantitation of tumor-infiltrating lymphocytes (TILs) allow, for the first time, the development of personalized cancer immunotherapies that target patient specific mutations. However, there is currently no [[bioinformatics]] solution that supports the integration of these heterogeneous datasets.
The [[clinical laboratory]] holds a central position in patient care, and as such, ensuring accurate [[laboratory]] test results is a necessity. Internal [[quality control]] (QC) ensures day-to-day laboratory consistency. However, unless practiced, the success of laboratory [[quality management system]]s (QMSs) cannot be achieved. This depends on the efforts and commitment of laboratory personnel for its implementation. Hence, the aim of this study was to find out the knowledge of internal QC for laboratory tests among laboratory personnel working in the Department of Biochemistry, B.P. Koirala Institute of Health Sciences (BPKIHS), a tertiary care center ... ('''[[Journal:Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study|Full article...]]''')<br />
 
''Recently featured'':
We have developed a bioinformatics platform – Personalized Oncology Suite (POS) – that integrates clinical data, NGS data and whole-slide bioimages from tissue sections. POS is a web-based platform that is scalable, flexible and expandable. The underlying database is based on a data warehouse schema, which is used to integrate [[information]] from different sources. POS stores clinical data, [[Genomics|genomic]] data (SNPs and INDELs identified from NGS analysis), and scanned whole-slide images. ('''[[Journal:Personalized Oncology Suite: Integrating next-generation sequencing data and whole-slide bioimages|Full article...]]''')<br />
{{flowlist |
 
* [[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study]]
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* [[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems]]
''Recently featured'': [[Journal:Incorporating domain knowledge in chemical and biomedical named entity recognition with word representations|Incorporating domain knowledge in chemical and biomedical named entity recognition with word representations]], [[Journal:Requirements for data integration platforms in biomedical research networks: A reference model|Requirements for data integration platforms in biomedical research networks: A reference model]], [[Journal:4273π: Bioinformatics education on low cost ARM hardware|4273π: Bioinformatics education on low cost ARM hardware]]
* [[Journal:Data management challenges for artificial intelligence in plant and agricultural research|Data management challenges for artificial intelligence in plant and agricultural research]]
}}

Revision as of 18:14, 6 May 2024

Fig1 Mishra JofNepMedAss23 61-258.png

"Knowledge of internal quality control for laboratory tests among laboratory personnel working in a biochemistry department of a tertiary care center: A descriptive cross-sectional study"

The clinical laboratory holds a central position in patient care, and as such, ensuring accurate laboratory test results is a necessity. Internal quality control (QC) ensures day-to-day laboratory consistency. However, unless practiced, the success of laboratory quality management systems (QMSs) cannot be achieved. This depends on the efforts and commitment of laboratory personnel for its implementation. Hence, the aim of this study was to find out the knowledge of internal QC for laboratory tests among laboratory personnel working in the Department of Biochemistry, B.P. Koirala Institute of Health Sciences (BPKIHS), a tertiary care center ... (Full article...)
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