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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 OConnor BMCInformatics2010 11-12.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Karaattuthazhathu NatJLabMed23 12-2.png|260px]]</div>
'''"[[Journal:SeqWare Query Engine: Storing and searching sequence data in the cloud|SeqWare Query Engine: Storing and searching sequence data in the cloud]]"'''
'''"[[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study]]"'''


Since the introduction of next-generation DNA sequencers the rapid increase in [[Sequencing|sequencer]] throughput, and associated drop in costs, has resulted in more than a dozen human [[Genomics|genomes]] being resequenced over the last few years. These efforts are merely a prelude for a future in which genome resequencing will be commonplace for both biomedical research and clinical applications. The dramatic increase in sequencer output strains all facets of computational infrastructure, especially databases and query interfaces. The advent of cloud computing, and a variety of powerful tools designed to process petascale datasets, provide a compelling solution to these ever increasing demands.
For the release of precise and accurate reports of [[Medical test|routine tests]], its necessary to follow a proper [[quality management system]] (QMS) in the [[clinical laboratory]]. As one of the most popular QMS tools for process improvement, Six Sigma techniques and tools have been accepted widely in the [[laboratory]] testing process. Six Sigma gives an objective assessment of analytical methods and instrumentation, measuring the outcome of a process on a scale of 0 to 6. Poor outcomes are measured in terms of defects per million opportunities (DPMO). To do the performance assessment of each clinical laboratory [[analyte]] by Six Sigma analysis and to plan and chart out a better, customized [[quality control]] (QC) plan for each analyte, according to its own sigma value ... ('''[[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Full article...]]''')<br />
 
''Recently featured'':
In this work, we present the [[SeqWare]] Query Engine which has been created using modern cloud computing technologies and designed to support databasing information from thousands of genomes. Our backend implementation was built using the highly scalable, NoSQL HBase database from the Hadoop project. We also created a web-based frontend that provides both a programmatic and interactive query interface and integrates with widely used genome browsers and tools. ('''[[Journal:SeqWare Query Engine: Storing and searching sequence data in the cloud|Full article...]]''')<br />
{{flowlist |
 
* [[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems]]
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* [[Journal:Data management challenges for artificial intelligence in plant and agricultural research|Data management challenges for artificial intelligence in plant and agricultural research]]
''Recently featured'': [[Journal:SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data|SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data]], [[Journal:Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline|Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline]], [[Journal:Benefits of the community for partners of open source vendors|Benefits of the community for partners of open source vendors]]
* [[Journal:A blockchain-driven IoT-based food quality traceability system for dairy products using a deep learning model|A blockchain-driven IoT-based food quality traceability system for dairy products using a deep learning model]]
}}

Revision as of 16:52, 29 April 2024

Fig1 Karaattuthazhathu NatJLabMed23 12-2.png

"Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study"

For the release of precise and accurate reports of routine tests, its necessary to follow a proper quality management system (QMS) in the clinical laboratory. As one of the most popular QMS tools for process improvement, Six Sigma techniques and tools have been accepted widely in the laboratory testing process. Six Sigma gives an objective assessment of analytical methods and instrumentation, measuring the outcome of a process on a scale of 0 to 6. Poor outcomes are measured in terms of defects per million opportunities (DPMO). To do the performance assessment of each clinical laboratory analyte by Six Sigma analysis and to plan and chart out a better, customized quality control (QC) plan for each analyte, according to its own sigma value ... (Full article...)
Recently featured: