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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Tsai JofPersMed2016 6-1.png|80px]]</div>
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'''"[[Journal:Bioinformatics workflow for clinical whole genome sequencing at Partners HealthCare Personalized Medicine|Bioinformatics workflow for clinical whole genome sequencing at Partners HealthCare Personalized Medicine]]"'''
'''"[[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems]]"'''


Effective implementation of precision medicine will be enhanced by a thorough understanding of each patient’s genetic composition to better treat his or her presenting symptoms or mitigate the onset of disease. This ideally includes the sequence [[information]] of a complete genome for each individual. At Partners HealthCare Personalized Medicine, we have developed a clinical process for whole genome sequencing (WGS) with application in both healthy individuals and those with disease. In this manuscript, we will describe our [[bioinformatics]] strategy to efficiently process and deliver [[Genomics|genomic]] data to geneticists for clinical interpretation. We describe the handling of data from FASTQ to the final variant list for clinical review for the final report. We will also discuss our methodology for validating this workflow and the cost implications of running WGS. ('''[[Journal:Bioinformatics workflow for clinical whole genome sequencing at Partners HealthCare Personalized Medicine|Full article...]]''')<br />
Public interest in where food comes from and how it is produced, processed, and distributed has increased over the last few decades, with even greater focus emerging during the [[COVID-19]] [[pandemic]]. Mounting evidence and experience point to disturbing weaknesses in our food systems’ abilities to support human livelihoods and wellbeing, and alarming long-term trends regarding both the environmental footprint of food systems and mounting vulnerabilities to shocks and stressors. How can we tackle the “wicked problems” embedded in a food system? More specifically, how can convergent research programs be designed and resulting knowledge implemented to increase inclusion, sustainability, and resilience within these complex systems ... ('''[[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Full article...]]''')<br />
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Revision as of 17:11, 22 April 2024

Fig1 Tomich Sustain23 15-8.png

"Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems"

Public interest in where food comes from and how it is produced, processed, and distributed has increased over the last few decades, with even greater focus emerging during the COVID-19 pandemic. Mounting evidence and experience point to disturbing weaknesses in our food systems’ abilities to support human livelihoods and wellbeing, and alarming long-term trends regarding both the environmental footprint of food systems and mounting vulnerabilities to shocks and stressors. How can we tackle the “wicked problems” embedded in a food system? More specifically, how can convergent research programs be designed and resulting knowledge implemented to increase inclusion, sustainability, and resilience within these complex systems ... (Full article...)
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