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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Bianchi FrontinGenetics2016 7.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Tomich Sustain23 15-8.png|260px]]</div>
'''"[[Journal:Integrated systems for NGS data management and analysis: Open issues and available solutions|Integrated systems for NGS data management and analysis: Open issues and available solutions]]"'''
'''"[[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems]]"'''


Next-generation sequencing (NGS) technologies have deeply changed our understanding of cellular processes by delivering an astonishing amount of data at affordable prices; nowadays, many biology [[laboratory|laboratories]] have already accumulated a large number of sequenced samples. However, managing and analyzing these data poses new challenges, which may easily be underestimated by research groups devoid of IT and quantitative skills. In this perspective, we identify five issues that should be carefully addressed by research groups approaching NGS technologies. In particular, the five key issues to be considered concern: (1) adopting a [[laboratory information management system]] (LIMS) and safeguard the resulting raw data structure in downstream analyses; (2) monitoring the flow of the data and standardizing input and output directories and file names, even when multiple analysis protocols are used on the same data; (3) ensuring complete traceability of the analysis performed; (4) enabling non-experienced users to run analyses through a graphical user interface (GUI) acting as a front-end for the pipelines; (5) relying on standard metadata to annotate the datasets, and when possible using controlled vocabularies, ideally derived from biomedical ontologies. ('''[[Journal:Integrated systems for NGS data management and analysis: Open issues and available solutions|Full article...]]''')<br />
Public interest in where food comes from and how it is produced, processed, and distributed has increased over the last few decades, with even greater focus emerging during the [[COVID-19]] [[pandemic]]. Mounting evidence and experience point to disturbing weaknesses in our food systems’ abilities to support human livelihoods and wellbeing, and alarming long-term trends regarding both the environmental footprint of food systems and mounting vulnerabilities to shocks and stressors. How can we tackle the “wicked problems” embedded in a food system? More specifically, how can convergent research programs be designed and resulting knowledge implemented to increase inclusion, sustainability, and resilience within these complex systems ... ('''[[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Full article...]]''')<br />
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Revision as of 17:11, 22 April 2024

Fig1 Tomich Sustain23 15-8.png

"Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems"

Public interest in where food comes from and how it is produced, processed, and distributed has increased over the last few decades, with even greater focus emerging during the COVID-19 pandemic. Mounting evidence and experience point to disturbing weaknesses in our food systems’ abilities to support human livelihoods and wellbeing, and alarming long-term trends regarding both the environmental footprint of food systems and mounting vulnerabilities to shocks and stressors. How can we tackle the “wicked problems” embedded in a food system? More specifically, how can convergent research programs be designed and resulting knowledge implemented to increase inclusion, sustainability, and resilience within these complex systems ... (Full article...)
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