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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Reisman EBioinformatics2016 12.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Tomich Sustain23 15-8.png|260px]]</div>
'''"[[Journal:A polyglot approach to bioinformatics data integration: A phylogenetic analysis of HIV-1|A polyglot approach to bioinformatics data integration: A phylogenetic analysis of HIV-1]]"'''
'''"[[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems]]"'''


As [[sequencing]] technologies continue to drop in price and increase in throughput, new challenges emerge for the management and accessibility of genomic sequence data. We have developed a pipeline for facilitating the storage, retrieval, and subsequent analysis of molecular data, integrating both sequence and metadata. Taking a polyglot approach involving multiple languages, libraries, and persistence mechanisms, sequence data can be aggregated from publicly available and local repositories. Data are exposed in the form of a RESTful web service, formatted for easy querying, and retrieved for downstream analyses. As a proof of concept, we have developed a resource for annotated HIV-1 sequences. Phylogenetic analyses were conducted for >6,000 HIV-1 sequences revealing spatial and temporal factors influence the evolution of the individual genes uniquely. Nevertheless, signatures of origin can be extrapolated even despite increased globalization. The approach developed here can easily be customized for any species of interest. ('''[[Journal:A polyglot approach to bioinformatics data integration: A phylogenetic analysis of HIV-1|Full article...]]''')<br />
Public interest in where food comes from and how it is produced, processed, and distributed has increased over the last few decades, with even greater focus emerging during the [[COVID-19]] [[pandemic]]. Mounting evidence and experience point to disturbing weaknesses in our food systems’ abilities to support human livelihoods and wellbeing, and alarming long-term trends regarding both the environmental footprint of food systems and mounting vulnerabilities to shocks and stressors. How can we tackle the “wicked problems” embedded in a food system? More specifically, how can convergent research programs be designed and resulting knowledge implemented to increase inclusion, sustainability, and resilience within these complex systems ... ('''[[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Full article...]]''')<br />
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Revision as of 17:11, 22 April 2024

Fig1 Tomich Sustain23 15-8.png

"Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems"

Public interest in where food comes from and how it is produced, processed, and distributed has increased over the last few decades, with even greater focus emerging during the COVID-19 pandemic. Mounting evidence and experience point to disturbing weaknesses in our food systems’ abilities to support human livelihoods and wellbeing, and alarming long-term trends regarding both the environmental footprint of food systems and mounting vulnerabilities to shocks and stressors. How can we tackle the “wicked problems” embedded in a food system? More specifically, how can convergent research programs be designed and resulting knowledge implemented to increase inclusion, sustainability, and resilience within these complex systems ... (Full article...)
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