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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:GA Karim JofKSUScience2022 34-2.jpg|240px]]</div>
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'''"[[Journal:Development of Biosearch System for biobank management and storage of disease-associated genetic information|Development of Biosearch System for biobank management and storage of disease-associated genetic information]]"'''
'''"[[Journal:GitHub as an open electronic laboratory notebook for real-time sharing of knowledge and collaboration|GitHub as an open electronic laboratory notebook for real-time sharing of knowledge and collaboration]]"'''


Databases and software are important to manage modern high-throughput [[Laboratory|laboratories]] and store clinical and [[Genome informatics|genomic information]] for [[quality assurance]]. Commercial software is expensive, with proprietary code issues, while academic versions have adaptation issues. Our aim was to develop an adaptable in-house software system that can store specimen- and disease-associated genetic information in [[biobank]]s to facilitate [[translational research]]. A prototype was designed per the research requirements, and computational tools were used to develop the software under three tiers, using Visual Basic and ASP.net for the presentation tier, SQL Server for the data tier, and Ajax and JavaScript for the business tier. We retrieved specimens from the biobank using this software and performed microarray-based transcriptomic analysis to detect differentially expressed genes (DEGs) ... ('''[[Journal:Development of Biosearch System for biobank management and storage of disease-associated genetic information|Full article...]]''')<br />
[[Electronic laboratory notebook]]s (ELNs) have expanded the utility of the paper [[laboratory notebook]] beyond that of a simple record keeping tool. Open ELNs offer additional benefits to the scientific community, including increased transparency, reproducibility, and [[Data integrity|integrity]]. A key element underpinning these benefits is facile and expedient knowledge sharing which aids communication and collaboration. In previous projects, we have used [[LabTrove]] and [[LabArchives, LLC|LabArchives]] as open ELNs, in partnership with GitHub (an open-source web-based platform originally developed for collaborative coding) for communication and discussion. Here we present our personal experiences using GitHub as the central platform for many aspects of the scientific process ... ('''[[Journal:GitHub as an open electronic laboratory notebook for real-time sharing of knowledge and collaboration|Full article...]]''')<br />
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Revision as of 16:20, 26 March 2024

Fig1 Scroggie DigDisc2023 2.gif

"GitHub as an open electronic laboratory notebook for real-time sharing of knowledge and collaboration"

Electronic laboratory notebooks (ELNs) have expanded the utility of the paper laboratory notebook beyond that of a simple record keeping tool. Open ELNs offer additional benefits to the scientific community, including increased transparency, reproducibility, and integrity. A key element underpinning these benefits is facile and expedient knowledge sharing which aids communication and collaboration. In previous projects, we have used LabTrove and LabArchives as open ELNs, in partnership with GitHub (an open-source web-based platform originally developed for collaborative coding) for communication and discussion. Here we present our personal experiences using GitHub as the central platform for many aspects of the scientific process ... (Full article...)
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