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'''"[[Journal:National and transnational security implications of asymmetric access to and use of biological data|National and transnational security implications of asymmetric access to and use of biological data]]"'''
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Wang BMCMedInfoDecMak2019 19-1.png|240px]]</div>
'''"[[Journal:Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory|Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory]]"'''


Biology and [[biotechnology]] have changed dramatically during the past 20 years, in part because of increases in computational capabilities and use of engineering principles to study biology. The advances in supercomputing, data storage capacity, and [[Cloud computing|cloud platforms]] enable scientists throughout the world to generate, analyze, share, and store vast amounts of data, some of which are biological and much of which may be used to understand the human condition, agricultural systems, evolution, and environmental ecosystems. These advances and applications have enabled: (1) the emergence of data science, which involves the development of new algorithms to analyze and [[Data visualization|visualize data]]; and (2) the use of engineering approaches to manipulate or create new biological organisms that have specific functions, such as production of industrial chemical precursors and development of environmental bio-based sensors. Several biological sciences fields harness the capabilities of computer, data, and engineering sciences, including synthetic biology, precision medicine, precision agriculture, and systems biology. These advances and applications are not limited to one country. This capability has economic and physical consequences but is vulnerable to unauthorized intervention. ('''[[Journal:National and transnational security implications of asymmetric access to and use of biological data|Full article...]]''')<br />
n autoverification system for coagulation consists of a series of rules that allows normal data to be released without manual verification. With new advances in [[medical informatics]], the [[laboratory information system]] (LIS) has growing potential for the use of autoverification, allowing rapid and accurate verification of [[clinical laboratory]] tests. The purpose of the study is to develop and evaluate a LIS-based autoverification system for validation and efficiency.
 
Autoverification decision rules—including quality control, analytical error flag, critical value, limited range check, delta check, and logical check rules, as well as patient’s historical information—were integrated into the LIS. Autoverification limit ranges was constructed based on 5% and 95% percentiles. The four most commonly used coagulation assays—prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (FBG)—were followed by the autoverification protocols. ('''[[Journal:Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory|Full article...]]''')<br />
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Revision as of 15:52, 11 November 2019

Fig1 Wang BMCMedInfoDecMak2019 19-1.png

"Design and evaluation of a LIS-based autoverification system for coagulation assays in a core clinical laboratory"

n autoverification system for coagulation consists of a series of rules that allows normal data to be released without manual verification. With new advances in medical informatics, the laboratory information system (LIS) has growing potential for the use of autoverification, allowing rapid and accurate verification of clinical laboratory tests. The purpose of the study is to develop and evaluate a LIS-based autoverification system for validation and efficiency.

Autoverification decision rules—including quality control, analytical error flag, critical value, limited range check, delta check, and logical check rules, as well as patient’s historical information—were integrated into the LIS. Autoverification limit ranges was constructed based on 5% and 95% percentiles. The four most commonly used coagulation assays—prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (FBG)—were followed by the autoverification protocols. (Full article...)

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