Journal:Digitalization concepts in academic bioprocess development
| Full article title | Digitalization concepts in academic bioprocess development |
|---|---|
| Journal | Engineering in Life Sciences |
| Author(s) | Habich, Tessa; Beutel, Sascha |
| Author affiliation(s) | Leibniz University Hannover |
| Primary contact | Email: beutel at iftc dot uni dash hannover dot de |
| Year published | 2024 |
| Volume and issue | 24(4) |
| Article # | 2300238 |
| DOI | 10.1002/elsc.202300238 |
| ISSN | 1618-2863 |
| Distribution license | Creative Commons Attribution-NonCommercial 4.0 International |
| Website | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elsc.202300238 |
| Download | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/elsc.202300238 (PDF) |
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This article should be considered a work in progress and incomplete. Consider this article incomplete until this notice is removed. |
Abstract
Digitalization with integrated devices, digital and physical assistants, automation, and simulation is setting a new direction for laboratory work. Even with complex research workflows, high staff turnover, and a limited budget, some laboratories have already shown that digitalization is indeed possible. However, academic bioprocess laboratories often struggle to follow the trend of digitalization. Due to their diverse research circumstances, high variety of team composition, goals, and limitations, the concepts are substantially different. Here, we will provide an overview on different aspects of digitalization and describe how academic laboratories successfully digitalized their working environment. The key aspect is the collaboration and communication between IT-experts and scientific staff. The developed digital infrastructure is only useful if it supports the laboratory worker and does not complicate their work. Thereby, laboratory researchers have to collaborate closely with IT experts in order for a well-developed and maintainable digitalization concept that fits their individual needs and level of complexity to emerge. This review may serve as a starting point or a collection of ideas for the transformation toward a digitalized bioprocess laboratory.
Keywords: academic laboratories, automation, bioprocess, digitalization, FAIR data, Laboratory and Analytical Device Standard (LADS), Standardization in Lab Automation 2 (SiLA2)
Introduction
Abbreviations, acronyms, and initialisms
- AI: artificial intelligence
- AR: augmented reality
- CLI: command line interface
- DoE: design of experiments
- ELN: electronic laboratory notebook
- FAIR: findable, accessible, interoperable, reusable
- GUI: graphical user interface
- IoT: internet of things
- LADS: Laboratory and Analytical Device Standard
- LIMS: laboratory information management system
- ML: machine learning
- NUI: natural user interface
- OPC UA: open platform communications unified architecture
- SiLA2: Standardization in Lab Automation 2
- VR: virtual reality
- VUI: voice user interface
References
Notes
This presentation is faithful to the original, with only a few minor changes to presentation. A fair amount of grammar and punctuation was updated from the original. In some cases important information was missing from the references, and that information was added.
