User:Shawndouglas/sandbox/sublevel4

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Toxicology Research at FDA (NCTR 1404) (6008498003).jpg

Test types in a toxicology lab will vary based on the lab’s focus, making the need for a LIMS that is flexible to the demands of toxicology labs essential. For example, toxicity testing on research animals may involve testing for acute toxicity, subacute toxicity, short-term subchronic toxicity, long-term chronic toxicity, reproductive toxicity, developmental toxicity, mutagenicity assays, irritation, allergic reaction, inhalation and immunotoxicity.[1] However, diagnostic testing will involve testing for drugs of abuse, poisons and heavy metals, or other toxicants. Pharmacogenetic testing may also be performed to develop dosing regiments for a specific drug.[2][3] Given the broad array of specialty analyses and workflows described, it makes sense that the toxicology LIMS will have to address these specific needs.

In addition to the essential features of a standard LIMS, the toxicology lab will also be looking for a system that can (or allows users to)[4][5][6][7][8]:

  • Support customizable drug panels and tests.
  • Support reference lab activities.
  • Track prescribed medicines and associated history.
  • Provide management for compounds and compound grouping.
  • Provide medication-based compliance monitoring and interpretive reporting on it.
  • Provide decision-support rules for pain management and toxicology.
  • Provide toxicology-specific reporting formats.
  • Manage drug court cases associated with testing.

References

  1. Eaton, D.L.; Gallagher, E.P. (2010). "Chapter 1.01 General Overview of Toxicology". In McQueen, C.A.. Comprehensive Toxicology (2nd ed.). Elsevier. pp. 1–46. ISBN 9780080468686. https://books.google.com/books?id=jzCAKsa2CpMC&pg=PA1. 
  2. "Clinical Toxicology Testing". ARUP Consult. ARUP Laboratories. June 2021. https://arupconsult.com/content/clinical-toxicology-testing. Retrieved 18 November 2021. 
  3. Sofronescu, A.G. (1 December 2018). "Purpose-driven Toxicology Services: The Key to Financial Success and Client Confidence". Clinical Laboratory News. American Association for Clinical Chemistry. https://www.aacc.org/cln/articles/2018/december/purpose-driven-toxicology-services-the-key-to-financial-success-and-client-confidence. Retrieved 09 March 2022. 
  4. "Easytox: Features". AP Easy Software Solutions. 2020. Archived from the original on 28 October 2020. https://web.archive.org/web/20201028074209/https://easytoxicology.com/features/. Retrieved 18 November 2021. 
  5. "Starfruit Toxicology". Data Unlimited International, Inc. 2021. http://www.duii.com/products/starfruit-toxicology/. Retrieved 18 November 2021. 
  6. "Toxicology LIMS". LabLynx, Inc. 2021. https://lablynx.com/toxicology/. Retrieved 18 November 2021. 
  7. "Online Data Management". DTPM, Inc. 2021. https://www.dtpm.com/online-data-management/. Retrieved 18 November 2021. 
  8. "Pain Management & Toxicology Labs". Orchard Software Corporation. 2021. https://www.orchardsoft.com/solutions/pain-management-toxicology-labs/. Retrieved 18 November 2021.