Immunoinformatics
History
Immunology researchers like Hans-Georg Rammensee trace the history of immunoinformatics back to the study of theoretical immunology. In June 1987, the Theoretical Immunology Workshop was hosted in Santa Fe, New Mexico to discuss "the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks."[1][2][3]
One of the first immunoinformatics efforts to result in a long-term informatics solution was the construction of the IMGT information system in 1989 by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM). Created to "standardize and manage the complexity of the immunogenetics data" coming out of the lab, the information system went on to become an international public reference for genetic and proteomic data related to immunology.[4]
Application
Immunoinformatics can help tackle problems and tasks such as the following[4]:
- improving the development of biological therapeutics
- developing and improving analysis and data management solutions for immunogenetics
- developing and improving allergen databases
- creating better computer models of the immune system
Informatics
See also
External links
References
- ↑ "Theoretical Immunology, Part One". Westview Press. http://westviewpress.com/books/theoretical-immunology-part-one/. Retrieved 20 January 2015.
- ↑ Rammensee, Hans-Georg; Novartis Foundation (2004). "Chair's introduction". Immunoinformatics: Bioinformatic Strategies for Better Understanding of Immune Function. John Wiley & Sons. pp. 1–2. ISBN 9780470090756. https://books.google.com/books?id=iBJc1JO1WuwC&pg=PA1. Retrieved 20 January 2015.
- ↑ Perelson, Alan S. (Ed.) (1988). Theoretical Immunology: The Proceedings of the Theoretical Immunology Workshop, held June 1987, in Santa Fe, New Mexico. 1 and 2. Addison-Wesley Pub. Co. pp. 811. ISBN 9780201156829. http://books.google.com/books/about/Theoretical_immunology.html?id=DxxrAAAAMAAJ. Retrieved 20 January 2015.
- ↑ 4.0 4.1 Schönbach, Christian; Ranganathan, Shoba; Brusic, Vladimir (Eds.) (2007). Immunoinformatics. Springer Science & Business Media. pp. 200. ISBN 9780387729671. https://books.google.com/books?id=YgjWcFng-4YC&pg=PA1. Retrieved 20 January 2015.
