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AB Sciex Pte. Ltd.
Main landing page for cannabis testing: https://sciex.com/applications/food-and-beverage-testing/cannabis-testing
Commonly known as Sciex, AB Sciex Pte. Ltd. develops "solutions in mass spectrometry paired with capillary electrophoresis and liquid chromatography."[1] The company markets some of its solutions for cannabis lab testing, including[2]:
- potency testing
- mycotoxin testing
- pesticide testing
- terpenes testing
Instruments and methods
Triple Quad systems
Sciex offers four different Triple Quad systems for tandem mass spectrometry paired with liquid chromatography (LC-MS/MS): the 6500+, 5500, 4500, and 3500. The company claims that with these systems "scientists can acquire multiple reaction monitoring (MRM), precursor, neutral loss, and product ion scans to develop powerful methods for complex matrices, all while maintaining reproducibility and robustness."[3]
QTRAP systems
Sciex also offers three different Triple Quad Linear Ion Traps (QTRAP) systems for LC-MS/MS: the 6500+, 5500, and 4500. The company states that these are similar to the Triple Quad systems "but with enhanced scan functions to enable simultaneous quantitation and confirmation."[4]
vMethod for Cannabis
Sciex also offers a "vMethod," a quantitation method for pesticide and cannabinoid analysis, that works on many of their LC-MS/MS systems.[5]
Agilent Technologies, Inc.
Main landing page for cannabis testing: https://www.agilent.com/en/promotions/cannabis
Agilent Technologies, Inc. is an instrument and software development company for the life sciences, diagnostics, and applied chemical industries. The company offers a variety of chromatography and spectrometry instruments (using a wide array of techniques) and software for the cannabis testing industry, including[6]:
- potency and efficacy testing
- heavy metals testing
- pesticide testing
- residual solvents testing
- terpenes testing
Instruments and methods
The company suggests instrument options based on what type of testing will occur.[6]
Potency and efficacy testing
- 1260 Infinity II SFC System: a supercritical fluid chromatography (SFC) system with an ultra-high performance liquid chromatography (UHPLC) power range
- 1290 Infinity II LC System: an UHPLC system
- 1290 Infinity II 2D-LC System: similar to the prior, but with two-dimensional liquid chromatography
- 5977B GC/MSD: a single-quadrupole GC/MS system with an electron ionization (EI) source
- Cary 630 FTIR Spectrometer: portable fourier-transform infrared (FTIR) spectroscopy
- Intuvo 9000 GC System: an ultra-fast gas chromatography system
Heavy metals testing
- 5110 ICP-OES Instrument: an inductively coupled plasma optical emission spectrometry (ICP-OES) instrument with synchronous radial and axial measurement
- 7800 ICP-MS: an inductively coupled plasma mass spectrometry (ICP-MS) instrument
- 7900 ICP-MS: an inductively coupled plasma mass spectrometry (ICP-MS) instrument with higher matrix tolerance, wider dynamic range, and better signal-to-noise ratio
- 8900 Triple Quadrupole ICP-MS: an inductively coupled plasma normal and tandem mass spectroscopy instrument with triple quadrupole
Pesticide testing
- 6400 Triple Quadrupole LC/MS: liquid chromatography normal and tandem mass spectrometry instruments, with four variations (6420A, -60C, -70A, and 95B)
- 6500 Series Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) LC/MS: quadrupole time-of-flight liquid chromatography-mass spectrometry instruments, with five variations (6530, -45, -45XT, -50, and -60)
- 7000D Triple Quadrupole GC/MS: a gas chromatography normal and tandem mass spectroscopy instrument with triple quadrupole and dynamic MRM
- GC/MS/MS Pesticides Analyzer: a gas chromatography tandem mass spectroscopy instrument with triple quadrupole
Residual solvents testing
- 7890 Series GC with 7697A Headspace Sampler and Flame Ionization Detector: a gas chromatography instrument combined with the 7697A Headspace Sampler and compatible flame ionization detector
Terpenes
- 1260 Infinity II Diode Array Detector HS: a liquid chromatography high-sensitivity diode array detector
- 1260 Infinity II Diode Array Detector WR: a liquid chromatography wide-range diode array detector
- 7890 Series GC: a gas chromatography instrument
- Intuvo 9000 GC System: an ultra-fast gas chromatography system
Software
- ICP Expert Software for ICP-OES: inductively coupled plasma optical emission spectrometry (ICP-OES) software for data analysis
- MassHunter: mass spectrometry software for instrument control, monitoring, and data analysis
- MicroLab: fourier-transform infrared spectroscopy software for quantitative method development, calibrations, and data analysis
References
- ↑ "About Us". AB Sciex Pte. Ltd. https://sciex.com/about-us. Retrieved 20 November 2018.
- ↑ "Grow Your Cannabis Lab's Potential and Bottom Line with LC-MS/MS Analysis". AB Sciex Pte. Ltd. https://sciex.com/applications/food-and-beverage-testing/cannabis-testing. Retrieved 20 November 2018.
- ↑ "Triple Quad LC-MS/MS Systems". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/triple-quad-systems. Retrieved 21 November 2018.
- ↑ "QTRAP LC-MS/MS Systems". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/qtrap-systems. Retrieved 21 November 2018.
- ↑ "vMethod Application for Quantitation of Pesticide Residues and Cannabinoids in Cannabis Matrices 1.0". AB Sciex Pte. Ltd. https://sciex.com/products/methods/vmethod-application-for-quantitation-of-pesticide-residues-and-cannabinoids-in-cannabis-matrices-10. Retrieved 21 November 2018.
- ↑ 6.0 6.1 "Cannabis Testing Solutions". Agilent Technologies, Inc. https://www.agilent.com/en/promotions/cannabis. Retrieved 21 November 2018.