Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Calabria BMCBioinformatics2015 16-Suppl9.jpg|220px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Signoroni NatComm23 14.png|240px]]</div>
'''"[[Journal:adLIMS: A customized open source software that allows bridging clinical and basic molecular research studies|adLIMS: A customized open source software that allows bridging clinical and basic molecular research studies]]"'''
'''"[[Journal:Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology|Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology]]"'''


Many biological laboratories that deal with genomic samples are facing the problem of sample tracking, both for pure [[laboratory]] management and for efficiency. Our laboratory exploits PCR techniques and Next Generation Sequencing (NGS) methods to perform high-throughput integration site monitoring in different clinical trials and scientific projects. Because of the huge amount of samples that we process every year, which result in hundreds of millions of sequencing reads, we need to standardize data management and tracking systems, building up a scalable and flexible structure with web-based interfaces, which are usually called [[Laboratory information management system|Laboratory Information Management System]] (LIMS).
Full [[laboratory automation]] is revolutionizing work habits in an increasing number of clinical [[microbiology]] facilities worldwide, generating huge streams of [[Imaging|digital images]] for interpretation. Contextually, [[deep learning]] (DL) architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic [[Bacteria|bacterial]] [[Cell culture|culture]] plates, including presumptive [[pathogen]] identification. This is achieved by decomposing the problem into a hierarchy of complex subtasks and addressing them with a multi-network architecture we call DeepColony ... ('''[[Journal:Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology|Full article...]]''')<br />
 
''Recently featured'':
We extended and customized [[ADempiere]] ERP to fulfill LIMS requirements and we developed adLIMS. It has been validated by our end-users verifying functionalities and GUIs through test cases for PCRs samples and pre-sequencing data and it is currently in use in our laboratories. adLIMS implements authorization and authentication policies, allowing multiple users management and roles definition that enables specific permissions, operations and data views to each user. ('''[[Journal:adLIMS: A customized open source software that allows bridging clinical and basic molecular research studies|Full article...]]''')<br />
{{flowlist |
 
* [[Journal:Critical analysis of the impact of AI on the patient–physician relationship: A multi-stakeholder qualitative study|Critical analysis of the impact of AI on the patient–physician relationship: A multi-stakeholder qualitative study]]
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* [[Journal:Judgements of research co-created by generative AI: Experimental evidence|Judgements of research co-created by generative AI: Experimental evidence]]
''Recently featured'': [[Journal:MendeLIMS: A web-based laboratory information management system for clinical genome sequencing|MendeLIMS: A web-based laboratory information management system for clinical genome sequencing]], [[Journal:Personalized Oncology Suite: Integrating next-generation sequencing data and whole-slide bioimages|Personalized Oncology Suite: Integrating next-generation sequencing data and whole-slide bioimages]], [[Journal:Incorporating domain knowledge in chemical and biomedical named entity recognition with word representations|Incorporating domain knowledge in chemical and biomedical named entity recognition with word representations]]
* [[Journal:Geochemical biodegraded oil classification using a machine learning approach|Geochemical biodegraded oil classification using a machine learning approach]]
}}

Latest revision as of 15:02, 3 June 2024

Fig1 Signoroni NatComm23 14.png

"Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology"

Full laboratory automation is revolutionizing work habits in an increasing number of clinical microbiology facilities worldwide, generating huge streams of digital images for interpretation. Contextually, deep learning (DL) architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic bacterial culture plates, including presumptive pathogen identification. This is achieved by decomposing the problem into a hierarchy of complex subtasks and addressing them with a multi-network architecture we call DeepColony ... (Full article...)
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