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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Pharma-production.jpg|160px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Signoroni NatComm23 14.png|240px]]</div>
'''[[Good Automated Manufacturing Practice]]''' ('''GAMP''') is both a technical subcommittee of the International Society for Pharmaceutical Engineering (ISPE) and a set of guidelines for manufacturers and users of automated systems in the pharmaceutical industry. One of the core principles of GAMP is that quality cannot be tested into a batch of product but must be built into each stage of the manufacturing process. As a result, GAMP covers all aspects of production; from the raw materials, facility and equipment to the training and hygiene of staff.
'''"[[Journal:Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology|Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology]]"'''


GAMP is largely about automated system validation. In October 2014, Irish tech company Dataworks Ltd. described it as such:
Full [[laboratory automation]] is revolutionizing work habits in an increasing number of clinical [[microbiology]] facilities worldwide, generating huge streams of [[Imaging|digital images]] for interpretation. Contextually, [[deep learning]] (DL) architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic [[Bacteria|bacterial]] [[Cell culture|culture]] plates, including presumptive [[pathogen]] identification. This is achieved by decomposing the problem into a hierarchy of complex subtasks and addressing them with a multi-network architecture we call DeepColony ... ('''[[Journal:Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology|Full article...]]''')<br />
 
''Recently featured'':
"It is a formal process of thorough documentation, testing, and logical process steps that validate clients' required specifications. The process begins with a user requirements specification for the machine, from which a functional requirement and a design specification are created. These documents then form the basis for the traceability matrix and for the formal testing of internal acceptance, factory acceptance, and site acceptance. Categorising software is used to support the approach to validation based on the difficulty and individuality of the computerised system." ('''[[Good Automated Manufacturing Practice|Full article...]]''')<br />
{{flowlist |
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* [[Journal:Critical analysis of the impact of AI on the patient–physician relationship: A multi-stakeholder qualitative study|Critical analysis of the impact of AI on the patient–physician relationship: A multi-stakeholder qualitative study]]
''Recently featured'': [[End-stage renal disease facility]], [[Genome informatics]], [[Cancer informatics]]
* [[Journal:Judgements of research co-created by generative AI: Experimental evidence|Judgements of research co-created by generative AI: Experimental evidence]]
* [[Journal:Geochemical biodegraded oil classification using a machine learning approach|Geochemical biodegraded oil classification using a machine learning approach]]
}}

Latest revision as of 15:02, 3 June 2024

Fig1 Signoroni NatComm23 14.png

"Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology"

Full laboratory automation is revolutionizing work habits in an increasing number of clinical microbiology facilities worldwide, generating huge streams of digital images for interpretation. Contextually, deep learning (DL) architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic bacterial culture plates, including presumptive pathogen identification. This is achieved by decomposing the problem into a hierarchy of complex subtasks and addressing them with a multi-network architecture we call DeepColony ... (Full article...)
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