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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Sachdeva Information22 13-2.png|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Berezin PLoSCompBio23 19-12.png|240px]]</div>
'''"[[Journal:Using knowledge graph structures for semantic interoperability in electronic health records data exchanges|Using knowledge graph structures for semantic interoperability in electronic health records data exchanges]]"'''
'''"[[Journal:Ten simple rules for managing laboratory information|Ten simple rules for managing laboratory information]]"'''
 
[[Information]] is the cornerstone of [[research]], from experimental data/[[metadata]] and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging [[laboratory information management system]]s (LIMS) to transform this large information load into useful scientific findings. The development of [[mathematical model]]s that can predict the properties of biological systems is the holy grail of [[computational biology]]. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... ('''[[Journal:Ten simple rules for managing laboratory information|Full article...]]''')<br />


[[Data sharing|Information sharing]] across medical institutions is restricted to [[information]] exchange between specific partners. The lifelong [[electronic health record]] (EHR) structure and content require standardization efforts. Existing standards such as [[openEHR]], [[Health Level 7]] (HL7), and ISO/EN 13606 aim to achieve data independence along with semantic interoperability. This study aims to discover knowledge representation to achieve semantic health data exchange. openEHR and ISO/EN 13606 use archetype-based technology for semantic interoperability. The HL7 Clinical Document Architecture is on its way to adopting this through HL7 templates. Archetypes are the basis for knowledge-based systems, as these are means to define clinical knowledge. The paper examines a set of formalisms for the suitability of describing, representing, and reasoning about archetypes. Each of the information exchange technologies—such as XML, Web Ontology Language (OWL), Object Constraint Language (OCL), and Knowledge Interchange Format (KIF)—is evaluated as a part of the knowledge representation experiment. These examine the representation of archetypes as described by Archetype Definition Language (ADL) ... ('''[[Journal:Using knowledge graph structures for semantic interoperability in electronic health records data exchanges|Full article...]]''')<br />
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Revision as of 18:03, 10 June 2024

Fig2 Berezin PLoSCompBio23 19-12.png

"Ten simple rules for managing laboratory information"

Information is the cornerstone of research, from experimental data/metadata and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging laboratory information management systems (LIMS) to transform this large information load into useful scientific findings. The development of mathematical models that can predict the properties of biological systems is the holy grail of computational biology. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... (Full article...)

Recently featured: