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'''"[[Journal:Learning health systems need to bridge the "two cultures" of clinical informatics and data science|Learning health systems need to bridge the "two cultures" of clinical informatics and data science]]"'''
'''"[[Journal:Ten simple rules for managing laboratory information|Ten simple rules for managing laboratory information]]"'''


United Kingdom (U.K.) health research policy and plans for population health management are predicated upon transformative knowledge discovery from operational "big data." Learning health systems require not only data but also feedback loops of knowledge into changed practice. This depends on [[Information management|knowledge management]] and application, which in turn depends upon effective system design and implementation. [[Health informatics|Biomedical informatics]] is the interdisciplinary field at the intersection of health science, social science, and information science and technology that spans this entire scope.
[[Information]] is the cornerstone of [[research]], from experimental data/[[metadata]] and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging [[laboratory information management system]]s (LIMS) to transform this large information load into useful scientific findings. The development of [[mathematical model]]s that can predict the properties of biological systems is the holy grail of [[computational biology]]. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... ('''[[Journal:Ten simple rules for managing laboratory information|Full article...]]''')<br />


In the U.K., the separate worlds of health data science ([[bioinformatics]], big data) and effective healthcare system design and implementation ([[Health informatics#Clinical informatics|clinical informatics]], "digital health") have operated as "two cultures." Much National Health Service and social care data is of very poor quality. Substantial research funding is wasted on data cleansing or by producing very weak evidence. There is not yet a sufficiently powerful professional community or evidence base of best practice to influence the practitioner community or the digital health industry. ('''[[Journal:Learning health systems need to bridge the "two cultures" of clinical informatics and data science|Full article...]]''')<br />
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Revision as of 18:03, 10 June 2024

Fig2 Berezin PLoSCompBio23 19-12.png

"Ten simple rules for managing laboratory information"

Information is the cornerstone of research, from experimental data/metadata and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging laboratory information management systems (LIMS) to transform this large information load into useful scientific findings. The development of mathematical models that can predict the properties of biological systems is the holy grail of computational biology. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... (Full article...)

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