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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:NCDN - CDN.png|280px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Berezin PLoSCompBio23 19-12.png|240px]]</div>
A '''[[content delivery network]]''' or '''content distribution network''' ('''CDN''') is a large distributed system of servers deployed in multiple data centers or "nodes" across the Internet. The goal of a CDN is to serve content to end-users with the intended benefit of reducing bandwidth costs, improving page load times, and/or increasing global availability of content. This is done by hosting the content on several servers, and when a user makes a request to CDN-hosted content, the domain name server (DNS) will resolve to an optimized server based on location, availability, cost, and other metrics.
'''"[[Journal:Ten simple rules for managing laboratory information|Ten simple rules for managing laboratory information]]"'''


Content providers such as media companies and e-commerce vendors pay CDN operators to deliver their content to their audience of end-users. In turn, a CDN pays Internet service providers (ISPs), carriers, and network operators for hosting its servers in their data centers. Besides better performance and availability, CDNs also offload the traffic served directly from the content provider's origin infrastructure, resulting in possible cost savings for the content provider. In addition, CDNs provide the content provider a degree of protection from denial-of-service (DoS) attacks by using their large distributed server infrastructure to absorb the traffic.
[[Information]] is the cornerstone of [[research]], from experimental data/[[metadata]] and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging [[laboratory information management system]]s (LIMS) to transform this large information load into useful scientific findings. The development of [[mathematical model]]s that can predict the properties of biological systems is the holy grail of [[computational biology]]. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... ('''[[Journal:Ten simple rules for managing laboratory information|Full article...]]''')<br />


An increasing number of ISPs have built their own CDNs to improve on-net content delivery, reduce demand on their own infrastructure, and generate revenues from content customers. Additionally, some companies such as Microsoft, Amazon, and Netflix have built their own CDNs to tie in with their own products. ('''[[Content delivery network |Full article...]]''')<br />
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Revision as of 18:03, 10 June 2024

Fig2 Berezin PLoSCompBio23 19-12.png

"Ten simple rules for managing laboratory information"

Information is the cornerstone of research, from experimental data/metadata and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging laboratory information management systems (LIMS) to transform this large information load into useful scientific findings. The development of mathematical models that can predict the properties of biological systems is the holy grail of computational biology. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... (Full article...)

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