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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Lymph_node_with_metastatic_melanoma_-_by_Gabriel_Caponetti,_MD.jpg|200px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Berezin PLoSCompBio23 19-12.png|240px]]</div>
'''[[Anatomical pathology]]''' (or '''Anatomic pathology''') is a medical specialty that is concerned with the gross, microscopic, chemical, immunologic, and molecular examination of organs, tissues, and whole bodies (as in autopsy) to determine the presence of disease. Italian scientist Giovanni Battista Morgagni is widely considered the founding father of anatomic pathology.
'''"[[Journal:Ten simple rules for managing laboratory information|Ten simple rules for managing laboratory information]]"'''


Anatomical pathology is one of two branches of pathology, the other being [[clinical pathology]], the diagnosis of disease through the laboratory analysis of bodily fluids. Often, pathologists practice both anatomical and clinical pathology, a combination known as general pathology. The distinction between anatomic and clinical pathology is increasingly blurred by the introduction of technologies that require new expertise and the need to provide patients and referring physicians with integrated diagnostic reports.
[[Information]] is the cornerstone of [[research]], from experimental data/[[metadata]] and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging [[laboratory information management system]]s (LIMS) to transform this large information load into useful scientific findings. The development of [[mathematical model]]s that can predict the properties of biological systems is the holy grail of [[computational biology]]. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... ('''[[Journal:Ten simple rules for managing laboratory information|Full article...]]''')<br />


The procedures used in anatomic pathology include gross examination, [[histopathology]], immunohistochemistry, ''in situ'' hybridization, [[cytopathology]], electron microscopy, tissue cytogenetics, and flow immunophenotyping. Anatomic pathology differs from clinical pathology in several ways, often led by the differentiation in [[laboratory]] workflow. ('''[[Anatomical pathology|Full article...]]''')<br />
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Revision as of 18:03, 10 June 2024

Fig2 Berezin PLoSCompBio23 19-12.png

"Ten simple rules for managing laboratory information"

Information is the cornerstone of research, from experimental data/metadata and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging laboratory information management systems (LIMS) to transform this large information load into useful scientific findings. The development of mathematical models that can predict the properties of biological systems is the holy grail of computational biology. Such models can be used to test biological hypotheses, guide the development of biomanufactured products, engineer new systems meeting user-defined specifications, and much more ... (Full article...)

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