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'''[[Clinical chemistry]]''' (sometimes referred to as '''chemical pathology''') is the area of [[clinical pathology]] that is generally concerned with analysis of bodily fluids. The discipline originated in the late nineteenth century with the use of simple chemical tests for various components of blood and urine. Subsequent to this, other techniques were applied including the use and measurement of enzyme activities, spectrophotometry, [[electrophoresis]], and [[immunoassay]].
'''[[Histopathology]]''' is a branch of histology and pathology that studies and diagnoses diseases on the tissue and cellular level. While histopathology is closely related to [[cytopathology]], the main difference is diagnostic information gained from histopathology is acquired from solid tissue samples, whereas specific disaggregated cell preparations are used in cytopathology. Typically a biopsy or surgical specimen is examined by a pathologist after the specimen has been processed and histological sections have been placed onto glass slides. Testing typically incorporates several stages, from collection and preparation using numerous methods (depending on the sample and test type) down to examination.


Today [[Clinical laboratory|clinical laboratories]] are now highly automated to accommodate the high workload typical of a hospital laboratory or [[reference laboratory]]. A large clinical laboratory will accept samples for up to about 700 different kinds of tests. Even the largest of laboratories rarely do all these tests themselves, and some must be referred to other labs. This large array of tests can be further sub-categorized into sub-specialties like general or routine chemistry, special chemistry, clinical endocrinology, [[toxicology]], therapeutic drug monitoring, urinalysis, and fecal analysis. ('''[[Clinical chemistry|Full article...]]''')<br />
Rudolf Ludwig Karl Virchow is considered by many to be one of the fathers of cellular pathology, remembered most for his collection of lectures on the topic, published as ''Cellular Pathology'' in 1858. However, his assistant, David Paul von Hansemann also played an important role in the progress of histopathology during the 1890s, producing his book ''The Microscopic Diagnosis of Malignant Tumours'' and other important research. ('''[[Histopathology|Full article...]]''')<br />
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''Recently featured'': [[Desktop virtualization]], [[Comprehensive outpatient rehabilitation facility]], [[National Institutes of Health]]
''Recently featured'': [[Clinical chemistry]], [[Desktop virtualization]], [[Comprehensive outpatient rehabilitation facility]]

Revision as of 19:10, 29 December 2014

Liver cyst wall - high mag.jpg

Histopathology is a branch of histology and pathology that studies and diagnoses diseases on the tissue and cellular level. While histopathology is closely related to cytopathology, the main difference is diagnostic information gained from histopathology is acquired from solid tissue samples, whereas specific disaggregated cell preparations are used in cytopathology. Typically a biopsy or surgical specimen is examined by a pathologist after the specimen has been processed and histological sections have been placed onto glass slides. Testing typically incorporates several stages, from collection and preparation using numerous methods (depending on the sample and test type) down to examination.

Rudolf Ludwig Karl Virchow is considered by many to be one of the fathers of cellular pathology, remembered most for his collection of lectures on the topic, published as Cellular Pathology in 1858. However, his assistant, David Paul von Hansemann also played an important role in the progress of histopathology during the 1890s, producing his book The Microscopic Diagnosis of Malignant Tumours and other important research. (Full article...)

Recently featured: Clinical chemistry, Desktop virtualization, Comprehensive outpatient rehabilitation facility